SCHEMBL20344729

SCHEMBL20344729

CCCNCc1ccccc1CCC=O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 1/20 0.40
MPO P05164 3/20 0.40
CA12 O43570 5/20 0.39
CA2 P00918 5/20 0.39
CHRM2 P08172 4/20 0.39
MOK Q9UQ07 1/20 0.37
CA9 Q16790 4/20 0.37
KDM4E B2RXH2 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GRIN1 Q05586 3/20 0.36
GRIN2A Q12879 3/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910304 0.81 ALDH1A1 (0.40) TSHRALDH1A1
Formic Acid SCHEMBL6326773 0.80 ALDH1A1 (0.44) MAOAMAOBSLC6A4SLC6A3MPO
SCHEMBL910692 0.79 GABRA1 (0.39) CHRM2TSHRALDH1A1
SCHEMBL28607303 0.79 ADH1B (0.36) MPOCHRM2TSHRALDH1A1
SCHEMBL3345733 0.78 TSHR (0.44) KDM4ETSHRHSD17B10
SCHEMBL30845912 0.78 TSHR (0.44) KDM4ETSHRHSD17B10
SCHEMBL20344737 0.77 MAOA (0.35) MAOAMAOBSLC6A4SLC6A3CA12
SCHEMBL20344730 0.77 MOK (0.35) MAOAMAOBMOKALDH1A1
SCHEMBL3693829 0.77 LIPG (0.50) KDM4ETSHRHSD17B10
Propionaldehyde SCHEMBL29282081 0.75 CYP3A4 (0.41) KDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3342766-A1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) 2018-07-04 EP disclosed