SCHEMBL20616477

SCHEMBL20616477

CCCn1c(=O)ccc2cc(NS(=O)(=O)Cc3ccc(C)cc3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 11/20 0.55
HDAC8 Q9BY41 2/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 1/20 0.42
BRD1 O95696 4/20 0.41
BRD4 O60885 2/20 0.41
BRD9 Q9H8M2 2/20 0.41
BRPF3 Q9ULD4 2/20 0.41
P2RX3 P56373 1/20 0.40
TP53 P04637 1/20 0.40
THRB P10828 1/20 0.40
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20344777 0.86 BRPF1 (0.50) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL20344752 0.84 BRPF1 (0.50) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL20616474 0.84 BRPF1 (0.47) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL20344791 0.83 BRPF1 (0.46) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL20344727 0.82 BRPF1 (0.52) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL22756346 0.81 BRPF1 (0.54) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL20344757 0.80 BRPF1 (0.50) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL24519726 0.79 P2RX3 (0.41) BRPF1MAPTLMNAPOLBBRD1
SCHEMBL20344719 0.78 BRPF1 (0.47) BRPF1HDAC8HDAC1HDAC6MAPT
SCHEMBL17979387 0.76 MAPT (0.45) BRPF1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398940-B1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2022-06-22 EP disclosed
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2021-08-03 US disclosed
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF BOLA2; BOLA2B, MYB, PPA1 BRPF1 388/4885HDAC8 1881/4885HDAC1 1384/4885
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof BOLA2; BOLA2B, MYB, PPA1 BRPF1 388/4885HDAC8 1881/4885HDAC1 1384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.