SCHEMBL203467

SCHEMBL203467

FC(F)(F)c1ccc2[nH]nnc2c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.44
PKM P14618 1/20 0.42
KIF11 P52732 8/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPK1 P28482 2/20 0.41
MAP2K4 P45985 2/20 0.41
MAPKAPK3 Q16644 2/20 0.41
MAPK6 Q16659 2/20 0.41
MAPKAPK2 P49137 1/20 0.41
PARP1 P09874 1/20 0.40
CHUK O15111 1/20 0.39
NPBWR1 P48145 2/20 0.38
BACE1 P56817 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27957536 0.87 GAA (0.33) METAP2PKMMAPK1MAP2K4MAPKAPK3
SCHEMBL7855617 0.85 MAPT (0.39) METAP2PKMKIF11KDM4EMAPK1
SCHEMBL7855336 0.85 METAP2 (0.49) METAP2KIF11KDM4ENPBWR1BACE1
SCHEMBL762335 0.81 KIF11 (0.41) METAP2PKMKIF11CHUK
SCHEMBL5720456 0.81 TSHR (0.38)
SCHEMBL23069661 0.79 CYP3A4 (0.30)
SCHEMBL10444103 0.78 FFAR1 (0.46) NPBWR1
SCHEMBL1843189 0.75 PARP1 (0.58) PKMKIF11KDM4EMAPK1MAP2K4
SCHEMBL6090810 0.75 LCK (0.39)
SCHEMBL1023455 0.75 NPC1 (0.38) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122041642-A Sewage treatment method based on cyclopentane heat exchange 广东石油化工学院 2026-05-15 CN claimed
US-12550694-B2 Selective deposition for integrated circuit interconnect structures TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2026-02-10 US claimed
US-12278143-B2 Method of providing a workpiece including low resistance interconnect low-resistance interconnect TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2025-04-15 US claimed
US-20240258166-A1 SELECTIVE DEPOSITION FOR INTEGRATED CIRCUIT INTERCONNECT STRUCTURES TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2024-08-01 US claimed
CN-117285985-A Low-dynamic surface tension insulating layer buffer cleaning liquid and preparation method and application thereof 四川格林达电子材料有限公司 2023-12-26 CN claimed
US-20230369114-A1 Low-Resistance Interconnect TAIWAN SEMICONDUCTOR MANUFACTORING CO., LTD (TW) 2023-11-16 US claimed
US-20220277996-A1 SELECTIVE DEPOSITION FOR INTEGRATED CIRCUIT INTERCONNECT STRUCTURES TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2022-09-01 US claimed
EP-0851282-B1 Processing of a light-sensitive silver halide photographic material AGFA GEVAERT (BE) 2003-04-16 EP claimed
US-5912108-A FORMING IMAGES BY EXPOSURE TO LIGHT ON SUPPORTS AGFA-GEVAERT, N.V. (BE) 1999-06-15 US claimed
EP-0851282-A1 Processing of a light-sensitive silver halide photographic material AGFA-GEVAERT N.V. (BE) 1998-07-01 EP claimed
CN-122041642-A Sewage treatment method based on cyclopentane heat exchange 广东石油化工学院 2026-05-15 CN disclosed
US-12550694-B2 Selective deposition for integrated circuit interconnect structures TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2026-02-10 US disclosed
US-20260033305-A1 LOW-RESISTANCE INTERCONNECT TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2026-01-29 US disclosed
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 EP disclosed
US-12482743-B2 Interconnect structure and method for forming the same TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2025-11-25 US disclosed
EP-0688217-A1 HETEROCYCLE-CONTAINING MACROCYCLIC IMMUNOMODULATORS ABBOTT LABORATORIES (US) 1995-12-27 EP disclosed
WO-1994021258-A1 HETEROCYCLE-CONTAINING MACROCYCLIC IMMUNOMODULATORS ABBOTT LABORATORIES (US) 1994-09-29 WO disclosed
EP-0617320-A2 Tabular grain emulsions containing antifoggants and stabilizers EASTMAN KODAK COMPANY (US) 1994-09-28 EP disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 US disclosed
US-4871653-A DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12550694-B2 Selective deposition for integrated circuit interconnect structures CAPRIN1, PIEZO1, GJB2 METAP2 4008/4885PKM 3966/4885KIF11 1260/4885
US-20260033305-A1 LOW-RESISTANCE INTERCONNECT CAPZB, CTCF, PIEZO1 METAP2 3301/4885PKM 3719/4885KIF11 2287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.