Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19007858 | 0.88 | ALDH1A1 (0.53) | TDP1LMNAL3MBTL1 | |
| SCHEMBL27481292 | 0.85 | HDAC3 (0.47) | CYP4F2CYP4A11TSHRLMNA | |
| SCHEMBL3252670 | 0.85 | CYP4F2 (0.45) | CYP4F2CYP4A11TDP1TSHRLMNA | |
| SCHEMBL6238563 | 0.85 | PPID (0.48) | PPIDCYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL23552019 | 0.84 | ALDH1A1 (0.50) | TSHRLMNA | |
| SCHEMBL12446348 | 0.84 | MMP8 (0.51) | MMP8SMN1; SMN2PPIDTSHRLMNA | |
| SCHEMBL7933675 | 0.84 | ALDH1A1 (0.50) | TSHRLMNA | |
| SCHEMBL27484931 | 0.83 | TSHR (0.44) | TSHR | |
| SCHEMBL23710194 | 0.82 | TDP1 (0.50) | TDP1TSHRLMNA | |
| SCHEMBL21214616 | 0.81 | ALOX5 (0.47) | MMP8ALOX5SMN1; SMN2PPIDCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122775-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2018-07-05 | — | — | WO | disclosed |