Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21214617 | 0.82 | CPA3 (0.57) | LTA4HALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL20355756 | 0.81 | MMP8 (0.49) | ALOX5SMN1; SMN2LTA4HMMP8CYP4F2 | |
| SCHEMBL28300615 | 0.76 | CPA3 (0.48) | ALOX5SMN1; SMN2MMP8ALDH1A1OPRK1 | |
| SCHEMBL28300614 | 0.76 | CPA3 (0.48) | ALOX5SMN1; SMN2MMP8ALDH1A1OPRK1 | |
| SCHEMBL10010705 | 0.76 | LTA4H (0.50) | SMN1; SMN2LTA4HOPRM1OPRD1OPRK1 | |
| Bromide SCHEMBL17550737 | 0.75 | L3MBTL1 (0.45) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL11117786 | 0.74 | OPRK1 (0.48) | OPRD1OPRK1 | |
| SCHEMBL15805201 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2MMP8ALDH1A1GAALMNA | |
| Bicarbonate SCHEMBL8168589 | 0.74 | CSNK1E (0.52) | OPRM1OPRD1OPRK1 | |
| Bicarbonate SCHEMBL8164473 | 0.74 | CSNK1E (0.52) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019144805-A1 | SUBSTITUTED PHENYLETHYLAMINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-08-01 | — | — | WO | disclosed |