SCHEMBL7933675

SCHEMBL7933675

COC(=O)CCC(C)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CA12 O43570 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TSHR P16473 1/20 0.45
THRB P10828 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
CPA3 P15088 1/20 0.44
CYSLTR2 Q9NS75 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23552019 1.00 ALDH1A1 (0.50) ALDH1A1KDM4ELMNANPC1RAB9A
SCHEMBL27487295 0.90 LMNA (0.48) ALDH1A1KDM4ELMNANPC1RAB9A
SCHEMBL27484931 0.85 TSHR (0.44) NPC1RAB9AMEN1KMT2ATSHR
SCHEMBL5934204 0.85 CA12 (0.52) ALDH1A1KDM4ELMNACA12CA7
SCHEMBL31650453 0.84 LDHA (0.54) ALDH1A1LMNAKMT2AHSD17B10
SCHEMBL19007858 0.84 ALDH1A1 (0.53) ALDH1A1LMNAMEN1KMT2ACYP2C9
SCHEMBL20355756 0.84 MMP8 (0.49) LMNATSHR
SCHEMBL10509525 0.83 NPC1 (0.51) ALDH1A1LMNANPC1RAB9AMEN1
SCHEMBL3440803 0.82 CPA3 (0.62) NPC1RAB9AMEN1KMT2ACPA3
SCHEMBL757260 0.82 CPA3 (0.62) NPC1RAB9AMEN1KMT2ACPA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112538400-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2021-03-23 CN claimed
WO-2022253101-A1 PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR 上海优理惠生医药有限公司 2022-12-08 WO disclosed
CN-112538400-A Vehicle-mounted fragrance and preparation method thereof 广州汽车集团股份有限公司 2021-03-23 CN disclosed
CN-1329365-C Indanes and indanones and their use in perfumery GIVAUDAN SA (CH) 2007-08-01 CN disclosed
CN-1615294-A Indanes and indanones and their use in perfumery GIVAUDAN SA (CH) 2005-05-11 CN disclosed
US-6310033-B1 2,4-DIMETHYL-5-PHENYLPENTANAL; PERFUMES BUSH BOAKE ALLEN INC. 2001-10-30 US disclosed