Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609596 | 0.88 | L3MBTL1 (0.47) | MTNR1BL3MBTL1KDM4EHDAC1HDAC6 | |
| SCHEMBL20357398 | 0.88 | L3MBTL1 (0.43) | MTNR1BL3MBTL1KDM4EHDAC1HDAC6 | |
| SCHEMBL18609826 | 0.87 | HDAC1 (0.56) | L3MBTL1KDM4EALDH1A1MAPTHDAC1 | |
| SCHEMBL18609814 | 0.87 | ALOX5 (0.49) | MTNR1BL3MBTL1HDAC1HDAC6PPARG | |
| SCHEMBL18609595 | 0.86 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1MAPTHDAC1 | |
| SCHEMBL18609598 | 0.85 | MCHR1 (0.51) | MTNR1BL3MBTL1HDAC1HDAC6PPARG | |
| SCHEMBL18609408 | 0.85 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTHDAC1HDAC6 | |
| SCHEMBL20608399 | 0.85 | MTNR1B (0.44) | MTNR1BL3MBTL1HDAC1HDAC6PPARG | |
| SCHEMBL18609825 | 0.85 | RXRA (0.53) | L3MBTL1ALDH1A1HDAC1HDAC6PPARG | |
| SCHEMBL20370805 | 0.83 | L3MBTL1 (0.42) | MTNR1BL3MBTL1MAPTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345892-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |