Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 3/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GALK1 | P51570 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL145372 | 0.93 | DNMT1 (0.43) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL8387982 | 0.89 | DNMT1 (0.34) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL8848720 | 0.86 | DNMT1 (0.39) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL21805762 | 0.86 | MAPT (0.40) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL4608905 | 0.85 | DNMT1 (0.43) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL8303 | 0.85 | DNMT1 (0.48) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL975384 | 0.85 | DNMT1 (0.38) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL1241564 | 0.84 | TP53 (0.36) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL10906735 | 0.84 | HTT (0.43) | DNMT1HTTSMN1; SMN2TP53MAPT | |
| Triaziquone SCHEMBL8926769 | 0.84 | DNMT1 (0.42) | DNMT1HTTSMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022745-A1 | Methods for Labeling a Population of RNA Molecules | NEW ENGLAND BIOLABS, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| US-20180195061-A1 | Methods for Labeling a Population of RNA Molecules | NEW ENGLAND BIOLABS, INC. (US) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195061-A1 | Methods for Labeling a Population of RNA Molecules | RNGTT, RNMT, MTAP | DNMT1 239/4885HTT 3101/4885SMN1; SMN2 2890/4885 |
| US-20230022745-A1 | Methods for Labeling a Population of RNA Molecules | RNGTT, RNMT, MTAP | DNMT1 239/4885HTT 3101/4885SMN1; SMN2 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.