Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 3/20 | 0.32 |
| ▸ | APAF1 | O14727 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL738610 | 0.90 | DNMT1 (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL20359693 | 0.85 | DNMT1 (0.39) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL4608905 | 0.84 | DNMT1 (0.43) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL8303 | 0.84 | DNMT1 (0.48) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL8926769 | 0.82 | DNMT1 (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL10906735 | 0.82 | HTT (0.43) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL7783197 | 0.82 | MAPT (0.46) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL149876 | 0.82 | MAPT (0.46) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL1975651 | 0.82 | DNMT1 (0.37) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL22716451 | 0.82 | HTT (0.38) | DNMT1HTTTP53MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711506-B1 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | VENCOREX FRANCE (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8173742-B2 | Synthesis of biurets and isocyanates with alkoxysilane functions, formulations containing same and use thereof | PERSTORP FRANCE (FR) | 2012-05-08 | — | — | US | disclosed |
| US-20110065957-A1 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | PERSTORP FRANCE (FR) | 2011-03-17 | — | — | US | disclosed |
| US-7875693-B2 | reacting hexamethylene diisocyanate with aminopropy/ltrimethoxysilane/3-/ to form intermediate isocyanatoalkylsilane and reacting the isocyanatoalkylsilane with an isocyanate to form a biuret | PERSTORP FRANCE (FR) | 2011-01-25 | — | — | US | disclosed |
| US-20070015895-A1 | Synthesis of biurets and isocyanates with alkoxysilane functions, formulations containing same and use thereof | RHODIA OPERATIONS (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1711506-A2 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | RHODIA CHIMIE (FR) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005070942-A2 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | RHODIA CHIMIE (FR) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065957-A1 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF | THEM6, INMT, BCAT2 | DNMT1 1454/4885HTT 1555/4885TP53 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.