Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20360396 | 0.98 | ALDH1A1 (0.46) | PRKDCALDH1A1KDM4EL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL15329342 | 0.81 | HTR7 (0.44) | ALDH1A1KDM4ETDP1TSHRRECQL | |
| SCHEMBL5487538 | 0.79 | HTR7 (0.41) | PRKDCALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL13039956 | 0.79 | HTR7 (0.67) | PRKDCALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL27876080 | 0.79 | HTR7 (0.67) | PRKDCALDH1A1KDM4EL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL27892728 | 0.78 | HTR7 (0.65) | PRKDCALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL5352962 | 0.77 | HTR7 (0.69) | ALDH1A1KDM4EL3MBTL1TDP1TSHR | |
| SCHEMBL28618211 | 0.73 | KDM4E (0.41) | PRKDCALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL16814931 | 0.72 | KEAP1 (0.46) | PRKDCALDH1A1KDM4EL3MBTL1HTR1A | |
| N-Methylpiperidine SCHEMBL28957034 | 0.71 | TSHR (0.49) | ALDH1A1KDM4ETSHRRECQLHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194775-A1 | COMPOUND HAVING AGONISTIC ACTIVITY ON SOMATOSTATIN RECEPTOR, AND USE THEREOF FOR MEDICAL PURPOSES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-07-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194775-A1 | COMPOUND HAVING AGONISTIC ACTIVITY ON SOMATOSTATIN RECEPTOR, AND USE THEREOF FOR MEDICAL PURPOSES | SSTR2, SSTR1, SSTR3 | PRKDC 4436/4885ALDH1A1 3249/4885KDM4E 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.