Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411537 | 0.73 | PDK2 (0.46) | KDM4EL3MBTL1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL20360705 | 0.73 | PRKDC (0.48) | KDM4EL3MBTL1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL20140426 | 0.73 | HTR6 (0.43) | KDM4EL3MBTL1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL20360396 | 0.71 | ALDH1A1 (0.46) | KDM4EL3MBTL1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL4603480 | 0.70 | BACE1 (0.42) | ALDH1A1HSD17B10HPGDMAPTTSHR | |
| SCHEMBL240017 | 0.70 | CA12 (0.44) | KDM4EL3MBTL1ALDH1A1TDP1HSD17B10 | |
| SCHEMBL27588099 | 0.70 | CA12 (0.41) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5294302 | 0.70 | HTR7 (0.53) | ALDH1A1LMNA | |
| SCHEMBL25221380 | 0.67 | BACE1 (0.39) | L3MBTL1ALDH1A1TDP1HSD17B10HPGD | |
| SCHEMBL238377 | 0.67 | ALDH1A1 (0.43) | KDM4EL3MBTL1ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164444-A | DOCK1 inhibiting compounds and uses thereof | 国立大学法人九州大学 | 2021-07-23 | — | — | CN | disclosed |