Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12360663 | 0.83 | TSHR (0.46) | RNPEPMETAP2METAP1ALDH1A1FOLH1 | |
| SCHEMBL11320412 | 0.81 | GABRR1 (0.40) | FOLH1TSHR | |
| SCHEMBL17845798 | 0.79 | — | — | |
| SCHEMBL24072795 | 0.79 | — | — | |
| SCHEMBL17017541 | 0.79 | RNPEP (0.39) | RNPEPMETAP2METAP1ALDH1A1FOLH1 | |
| SCHEMBL15382734 | 0.79 | RNPEP (0.39) | RNPEPMETAP2METAP1ALDH1A1FOLH1 | |
| SCHEMBL18255116 | 0.78 | RNPEP (0.42) | RNPEPMETAP2METAP1ALDH1A1FOLH1 | |
| SCHEMBL7288155 | 0.77 | CTSC (0.41) | RNPEPMETAP2METAP1LMNATSHR | |
| SCHEMBL6690311 | 0.77 | CTSC (0.41) | RNPEPMETAP2METAP1LMNATSHR | |
| SCHEMBL6850456 | 0.77 | RNPEP (0.41) | RNPEPALDH1A1LMNATSHRCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194804-A1 | SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)- 1,4-DIKETOPIPERAZINE | EVONIK DEGUSSA GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194804-A1 | SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)- 1,4-DIKETOPIPERAZINE | METAP2, MTX2, METTL3 | RNPEP 1823/4885METAP2 1/4885METAP1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.