Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.88 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.88 |
| ▸ | USP2 | O75604 | 1/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.88 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.88 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.73 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | IL6 | P05231 | 1/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.56 |
| ▸ | GLUL | P15104 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421286 | 1.00 | PGR (0.88) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11438434 | 0.96 | PGR (0.87) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11431313 | 0.95 | NR3C1 (0.80) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11422089 | 0.94 | PGR (0.78) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11422219 | 0.94 | PGR (0.78) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL1650745 | 0.94 | NR3C1 (1.00) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL3941 | 0.94 | NR3C1 (1.00) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL3942 | 0.94 | NR3C1 (1.00) | PGRNR3C1HIF1ALMNACYP3A4 | |
| Prednicarbate SCHEMBL5483489 | 0.94 | NR3C1 (1.00) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL11425522 | 0.93 | NR3C1 (0.89) | PGRNR3C1HIF1ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180193486-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | CERULEAN PHARMA INC. | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180193486-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | PHOSPHO1, SGMS1, SGMS2 | PGR 2999/4885NR3C1 2698/4885HIF1A 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.