Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 3/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442144 | 1.00 | GABRR1 (0.38) | GABRR1DPP7RRM1BMP1GABBR2 | |
| SCHEMBL25556371 | 0.87 | MMP1 (0.40) | DPP7RRM1BMP1MMP9DPP8 | |
| SCHEMBL7980257 | 0.85 | SIRT6 (0.43) | DPP7MMP9DPP8DPP9MMP1 | |
| SCHEMBL12264542 | 0.85 | SIRT6 (0.43) | DPP7MMP9DPP8DPP9MMP1 | |
| SCHEMBL24728547 | 0.82 | KISS1R (0.37) | BMP1MMP9MMP2MMP8 | |
| SCHEMBL10442385 | 0.81 | — | — | |
| SCHEMBL17623529 | 0.81 | SIRT6 (0.46) | GABRR1BMP1MMP9MMP1MMP3 | |
| SCHEMBL13367162 | 0.81 | SIRT6 (0.46) | GABRR1BMP1MMP9MMP1MMP3 | |
| SCHEMBL16572822 | 0.79 | GABRR1 (0.33) | GABRR1DPP7RRM1BMP1 | |
| SCHEMBL12157041 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233889-B1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | SHANGHAI MICURX PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |