Biphenyl

Biphenyl

SCHEMBL2037133

C1CCC(C2CCCCC2)CC1.CCOCC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
SHBG P04278 1/20 0.36
CYP1A2 P05177 1/20 0.35
KDM4E B2RXH2 2/20 0.31
EPHX1 P07099 1/20 0.31
THRB P10828 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
POLB P06746 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL9725961 1.00 ALDH1A1 (0.47) ALDH1A1SHBGCYP1A2KDM4EEPHX1
Ether SCHEMBL8824885 1.00 ALDH1A1 (0.47) ALDH1A1SHBGCYP1A2KDM4EEPHX1
Biphenyl SCHEMBL6377422 0.90 ALDH1A1 (0.40) ALDH1A1SHBGCYP1A2KDM4EEPHX1
Biphenyl SCHEMBL11815560 0.88 TSHR (0.46) ALDH1A1SHBGEPHX1THRBATM
Biphenyl SCHEMBL10811203 0.88 ALDH1A1 (0.36) ALDH1A1SHBG
Cyclohexane SCHEMBL11165183 0.82 ALDH1A1 (0.40) ALDH1A1KDM4EEPHX1THRBATM
SCHEMBL10447633 0.81 ALDH1A1 (0.35) ALDH1A1CYP1A2
Biphenyl SCHEMBL3001877 0.81 ALDH1A1 (0.61) ALDH1A1SHBGCYP1A2ADH1CADH1A
Cyclohexane SCHEMBL8441380 0.80 ALDH1A1 (0.39) ALDH1A1
Cyclohexane SCHEMBL8441382 0.80 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160368844-A1 Process for Producing Mixtures of Cyclohexanone and Cyclohexanol EXXONMOBIL CHEMICAL PATENTS INC. 2016-12-22 US disclosed
EP-3024808-A1 PROCESS FOR PRODUCING MIXTURES OF CYCLOHEXANONE AND CYCLOHEXANOL ExxonMobil Chemical Patents Inc. (US) 2016-06-01 EP disclosed
WO-2015013017-A1 PROCESS FOR PRODUCING MIXTURES OF CYCLOHEXANONE AND CYCLOHEXANOL EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-01-29 WO disclosed
US-20110141418-A1 LIQUID CRYSTAL COMPOUNDS QINETIQ LIMITED (GB) 2011-06-16 US disclosed
WO-2010012994-A1 LIQUID CRYSTAL COMPOUNDS QINETIQ LIMITED (GB) 2010-02-04 WO disclosed
US-5108573-A Anchor of thio or halo compound to improve adhesion of polymer to metal substrate; high density THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1992-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110141418-A1 LIQUID CRYSTAL COMPOUNDS HTR3D, HTR3C, SFXN3 ALDH1A1 4679/4885SHBG 2347/4885CYP1A2 3757/4885
US-20160368844-A1 Process for Producing Mixtures of Cyclohexanone and Cyclohexanol KHK, BCKDK, HYPK ALDH1A1 4271/4885SHBG 2671/4885CYP1A2 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.