Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373416 | 0.74 | ADRB2 (0.40) | ADRB2ADRB1DRD2 | |
| SCHEMBL21573556 | 0.68 | ADRB2 (0.41) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL21573519 | 0.65 | ADRB2 (0.61) | ADRB2ADRB1DRD2 | |
| SCHEMBL18946397 | 0.64 | ADRB1 (0.43) | KDM4EADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL21573584 | 0.64 | ADRB2 (0.51) | ADRB2 | |
| SCHEMBL21573516 | 0.63 | ADRB2 (0.73) | ADRB2ADRB1 | |
| SCHEMBL19903891 | 0.61 | ADRB2 (0.40) | KDM4ETDP1ADRB2ADRB1DRD2 | |
| SCHEMBL23223708 | 0.61 | ADRB2 (0.42) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL20833606 | 0.60 | KDM4E (0.49) | KDM4ETDP1ADRB2ADRB1ADRA1D | |
| SCHEMBL20833607 | 0.60 | KDM4E (0.49) | KDM4ETDP1ADRB2ADRB1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |