Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 16/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373754 | 0.84 | TLR7 (0.37) | — | |
| SCHEMBL20373274 | 0.79 | PDE5A (0.38) | HDAC1HDAC8HDAC6 | |
| SCHEMBL16905814 | 0.72 | HDAC1 (0.39) | HDAC1HDAC8HDAC6 | |
| SCHEMBL20373449 | 0.71 | SYK (0.38) | — | |
| SCHEMBL20373789 | 0.70 | PDE10A (0.41) | — | |
| SCHEMBL18326367 | 0.69 | HDAC1 (0.39) | P2RX3HDAC1HDAC8HDAC6 | |
| SCHEMBL20373766 | 0.65 | GPR84 (0.36) | — | |
| SCHEMBL20373361 | 0.65 | AVPR2 (0.34) | — | |
| SCHEMBL20373288 | 0.64 | S1PR3 (0.37) | — | |
| SCHEMBL16896897 | 0.63 | BRD4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092227-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORP (FI) | 2018-07-11 | — | — | EP | disclosed |