Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373789 | 0.84 | PDE10A (0.41) | KMT2A | |
| SCHEMBL20373758 | 0.79 | P2RX3 (0.35) | HDAC1HDAC8HDAC6 | |
| SCHEMBL20373449 | 0.79 | SYK (0.38) | PDE5A | |
| SCHEMBL20373766 | 0.79 | GPR84 (0.36) | PDE5A | |
| SCHEMBL20373445 | 0.77 | TLR7 (0.33) | KMT2A | |
| SCHEMBL20373452 | 0.77 | KCNA5 (0.40) | PDE5AKMT2A | |
| SCHEMBL20373284 | 0.77 | KDM4E (0.36) | CSF1RMCHR1 | |
| SCHEMBL20373279 | 0.76 | PDE1A (0.40) | KMT2A | |
| SCHEMBL20373360 | 0.75 | MET (0.40) | KMT2AMCHR1 | |
| SCHEMBL20373754 | 0.74 | TLR7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092227-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORP (FI) | 2018-07-11 | — | — | EP | disclosed |