Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20376461 | 0.83 | CYP1A2 (0.38) | RIPK1HTR4HTR2CHTR7HTR2B | |
| SCHEMBL21690530 | 0.81 | FFAR4 (0.38) | HTR4HTR2CHTR7HTR2BHTR3A | |
| SCHEMBL21325057 | 0.80 | RIPK1 (0.37) | RIPK1HTR4HTR2CHTR7HTR2B | |
| SCHEMBL21534011 | 0.78 | HTR2C (0.36) | HTR4HTR2CHTR7HTR2BHTR3A | |
| SCHEMBL21325059 | 0.77 | PDE3B (0.35) | HTR4HTR2CHTR7HTR2BHTR3A | |
| SCHEMBL24180084 | 0.75 | RIPK1 (0.37) | RIPK1PARP15PARP10ALOX5APFEN1 | |
| SCHEMBL21690529 | 0.74 | ALOX5AP (0.34) | HTR4HTR2CHTR7HTR2BHTR3A | |
| SCHEMBL22371226 | 0.72 | MAOB (0.40) | RIPK1HTR2CHTR2BALOX5APFEN1 | |
| SCHEMBL30468385 | 0.72 | MAOB (0.40) | RIPK1HTR2CHTR2BALOX5APFEN1 | |
| SCHEMBL22390611 | 0.71 | RIPK1 (0.60) | RIPK1HTR4HTR2CHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247984-B2 | Uracil containing compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | RIPK1 3431/4885HTR4 4094/4885HTR2C 4038/4885 |
| US-11247984-B2 | Uracil containing compounds | UNG, DPYD, DUT | RIPK1 3431/4885HTR4 4094/4885HTR2C 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.