Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385145 | 0.90 | KCNN4 (0.41) | KCNN4ALOX5APFEN1ALDH1A1HTT | |
| SCHEMBL20385150 | 0.88 | ALDH1A1 (0.38) | KCNN4ALDH1A1HTTPOLBHPGD | |
| SCHEMBL20385149 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HTTPOLBHPGDNPC1 | |
| SCHEMBL20385086 | 0.84 | KCNN4 (0.43) | KCNN4ALDH1A1HTTPOLBNPC1 | |
| SCHEMBL20385147 | 0.83 | HPGD (0.48) | ALDH1A1HTTHPGDNPC1L3MBTL1 | |
| SCHEMBL20385159 | 0.82 | KCNN4 (0.45) | KCNN4ALDH1A1HTTNPC1L3MBTL1 | |
| SCHEMBL20385148 | 0.81 | HTT (0.44) | ALDH1A1HTTPOLBNPC1L3MBTL1 | |
| SCHEMBL20385085 | 0.78 | HTT (0.42) | ALDH1A1HTTPOLBNPC1KMT2A | |
| SCHEMBL20385160 | 0.77 | HTT (0.41) | ALDH1A1HTTPOLBHPGDNPC1 | |
| SCHEMBL20385132 | 0.76 | HPGD (0.48) | ALDH1A1HTTHPGDNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |