Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385150 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HPGDHTTL3MBTL1KMT2A | |
| SCHEMBL20385147 | 0.84 | HPGD (0.48) | ALDH1A1HPGDHTTL3MBTL1KMT2A | |
| SCHEMBL20385143 | 0.84 | KCNN4 (0.41) | ALDH1A1HPGDHTTL3MBTL1KMT2A | |
| SCHEMBL20385159 | 0.83 | KCNN4 (0.45) | ALDH1A1HTTL3MBTL1KMT2ANPC1 | |
| SCHEMBL20385086 | 0.83 | KCNN4 (0.43) | ALDH1A1HTTL3MBTL1KMT2ANPC1 | |
| SCHEMBL20385148 | 0.80 | HTT (0.44) | ALDH1A1HTTL3MBTL1KMT2ANPC1 | |
| SCHEMBL20385130 | 0.80 | KDM4E (0.40) | ALDH1A1HTTL3MBTL1KMT2ANPC1 | |
| SCHEMBL20385132 | 0.78 | HPGD (0.48) | ALDH1A1HPGDHTTKMT2ANPC1 | |
| SCHEMBL20385085 | 0.77 | HTT (0.42) | ALDH1A1HTTKMT2ANPC1MEN1 | |
| SCHEMBL20385160 | 0.76 | HTT (0.41) | ALDH1A1HPGDHTTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |