Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872721 | 0.84 | BCHE (0.41) | BCHECNR2DRD2LMNADDB1 | |
| SCHEMBL15600669 | 0.84 | KDM4E (0.51) | BRD4BCHECNR2DRD2KDM4E | |
| SCHEMBL17525438 | 0.73 | CYP1B1 (0.51) | BRD4BCHECNR2KDM4EALDH1A1 | |
| SCHEMBL21242001 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL4392860 | 0.71 | MALT1 (0.49) | BRD4BCHECNR2DRD2LMNA | |
| SCHEMBL17522974 | 0.71 | MEN1 (0.46) | BRD4BCHECNR2ALDH1A1L3MBTL1 | |
| SCHEMBL20385846 | 0.71 | LMNA (0.41) | BRD4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL25719625 | 0.68 | GAA (0.58) | BCHECNR2ALDH1A1MALT1 | |
| SCHEMBL25936945 | 0.68 | TPSAB1 (0.41) | DRD2ALDH1A1LMNADDB1CRBN | |
| SCHEMBL15600752 | 0.68 | MEN1 (0.49) | BRD4BCHECNR2DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3348555-B1 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | ALUMEND LLC (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3348555-A2 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | Alumend, LLC (US) | 2018-07-18 | — | — | EP | disclosed |