Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340532 | 0.78 | MEN1 (0.49) | KDM4EALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL12939880 | 0.77 | L3MBTL1 (0.58) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL27960801 | 0.77 | L3MBTL1 (0.58) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL6887733 | 0.77 | ALDH1A1 (0.74) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL19976649 | 0.73 | L3MBTL1 (0.57) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL20385853 | 0.72 | BRD4 (0.41) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL7632891 | 0.72 | L3MBTL1 (0.56) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL11932614 | 0.72 | ALDH1A1 (0.70) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL3888669 | 0.72 | ALDH1A1 (0.70) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL20392828 | 0.71 | STAT3 (0.48) | KDM4EALDH1A1LMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851185-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190241680-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851185-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | BMP2, SUN2, TAGLN2 | KDM4E 2869/4885ALDH1A1 1456/4885LMNA 383/4885 |
| US-20190241680-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | BMP2, SUN2, TAGLN2 | KDM4E 2869/4885ALDH1A1 1456/4885LMNA 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.