Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800448 | 0.79 | L3MBTL1 (0.45) | L3MBTL1TOP1LMNAHPGDALDH1A1 | |
| SCHEMBL7812932 | 0.74 | L3MBTL1 (0.51) | L3MBTL1TOP1LMNAHPGDALDH1A1 | |
| SCHEMBL25936947 | 0.74 | AKT1 (0.44) | SIGMAR1DRD2HPGDALDH1A1 | |
| SCHEMBL23653517 | 0.71 | LMNA (0.42) | MALT1L3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL24257250 | 0.71 | SYK (0.46) | TPSAB1TPSD1TPSG1MALT1L3MBTL1 | |
| SCHEMBL23762489 | 0.71 | L3MBTL1 (0.43) | L3MBTL1TOP1LMNAHPGDALDH1A1 | |
| SCHEMBL24627921 | 0.71 | MEN1 (0.47) | TPSAB1TPSD1TPSG1MALT1SIGMAR1 | |
| SCHEMBL24702203 | 0.69 | RAB9A (0.40) | MALT1L3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL24701949 | 0.69 | RAB9A (0.40) | MALT1L3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL18998206 | 0.69 | HPGD (0.46) | L3MBTL1LMNAHPGDALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147328-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |