SCHEMBL20394059

SCHEMBL20394059

CC(=O)OC1O[C@@](COCc2ccccc2)(C(C)N=[N+]=[N-])[C@@H](OCc2ccccc2)[C@H]1OC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ METAP2 P50579 2/20 0.33
▸ CAPN1 P07384 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ PTPN1 P18031 1/20 0.31
▸ CDC25B P30305 1/20 0.31
▸ GSTP1 P09211 2/20 0.31
▸ PSMB1 P20618 1/20 0.31
▸ PSMB5 P28074 1/20 0.31
▸ PSMB2 P49721 1/20 0.31
▸ PDPK1 O15530 1/20 0.31
▸ MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30689540 0.85 ALDH1A1 (0.35) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL25435703 0.84 ALDH1A1 (0.36) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL19492149 0.84 ALDH1A1 (0.36) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL20394018 0.81 ALDH1A1 (0.35) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL20272046 0.81 ALDH1A1 (0.35) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL20394084 0.81 TK1 (0.36) BCHECYP2D6LMNA
SCHEMBL20756448 0.79 ALDH1A1 (0.37) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL23152976 0.79 ALDH1A1 (0.37) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL23153000 0.79 BCHE (0.33) BCHEALDH1A1CYP2D6MAPK1METAP2
SCHEMBL19101763 0.78 LMNA (0.39) BCHEALDH1A1CYP2D6MAPK1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351548-B1 CROSSLINKED NUCLEIC ACID GUNA, METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND MITSUBISHI TANABE PHARMA CORP (JP) 2025-08-20 — — EP disclosed
EP-3974436-A1 CROSSLINKED NUCLEIC ACID GUNA METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND Mitsubishi Tanabe Pharma Corporation (JP) 2022-03-30 — — EP disclosed
US-10961269-B2 Bridged nucleic acid GuNA, method for producing same, and intermediate compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2021-03-30 — — US disclosed
US-20180251488-A1 CROSSLINKED NUCLEIC ACID GUNA, METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2018-09-06 — — US disclosed
EP-3351548-A1 CROSSLINKED NUCLEIC ACID GUNA, METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND Mitsubishi Tanabe Pharma Corporation (JP) 2018-07-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961269-B2 Bridged nucleic acid GuNA, method for producing same, and intermediate compound POLRMT, POLM, NSUN2 BCHE 4041/4885ALDH1A1 808/4885CYP2D6 3468/4885
US-20180251488-A1 CROSSLINKED NUCLEIC ACID GUNA, METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND NSUN2, RNMT, POLRMT BCHE 4402/4885ALDH1A1 1062/4885CYP2D6 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback