Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 4/20 | 0.38 |
| ▸ | ADH1A | P07327 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192507 | 0.86 | ADH1B (0.33) | ALDH1A1ADH1BADH1AADH7ADH1C | |
| SCHEMBL28217789 | 0.81 | — | — | |
| SCHEMBL27865718 | 0.77 | NPC1 (0.38) | NPC1S1PR2S1PR4ALDH1A1LMNA | |
| SCHEMBL28325410 | 0.74 | CA1 (0.43) | NPC1S1PR2S1PR4ALDH1A1LMNA | |
| SCHEMBL27684502 | 0.73 | NPC1 (0.43) | NPC1S1PR2S1PR4ALDH1A1LMNA | |
| SCHEMBL2384895 | 0.71 | HPGD (0.44) | NPC1S1PR2S1PR4ALDH1A1LMNA | |
| SCHEMBL19459592 | 0.70 | ZDHHC20 (0.43) | NPC1S1PR2S1PR4ALDH1A1LMNA | |
| SCHEMBL28082301 | 0.70 | FAAH (0.46) | CA1CA2CA12CA7CA14 | |
| SCHEMBL8746573 | 0.69 | NPC1 (0.32) | NPC1S1PR2S1PR4ALDH1A1LMNA | |
| SCHEMBL5122647 | 0.69 | CA2 (0.36) | NPC1S1PR2S1PR4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273808-B2 | Dispersing agents for gypsum plaster compositions | SIKA TECHNOLOGY AG (CH) | 2012-09-25 | — | — | US | disclosed |
| US-20110160351-A1 | DISPERSING AGENTS FOR GYPSUM PLASTER COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2011-06-30 | — | — | US | disclosed |