Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 3/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20399786 | 1.00 | OPRK1 (0.34) | OPRK1OPRD1KDM4EMITFHSP90AA1 | |
| SCHEMBL21528222 | 0.80 | JAK2 (0.42) | KDM4E | |
| SCHEMBL28196771 | 0.77 | POLB (0.33) | — | |
| SCHEMBL12142325 | 0.76 | METAP1 (0.33) | MITFHSP90AA1METAP1CCR6 | |
| SCHEMBL3169586 | 0.74 | FAAH (0.42) | — | |
| SCHEMBL9052963 | 0.72 | TACR3 (0.43) | KDM4E | |
| SCHEMBL15352654 | 0.72 | TACR3 (0.43) | KDM4E | |
| SCHEMBL21081462 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL22634130 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL504706 | 0.72 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136546-A1 | SUBSTITUTED 3-DIALKYLAMINOMETHYL-PIPERIDIN-4-YL-BENZAMIDES AND METHODS OF MAKING AND USING SAME | MEBIAS DISCOVERY LLC (US) | 2018-07-26 | — | — | WO | disclosed |