Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20400674 | 0.84 | HSD17B1 (0.46) | HSD17B1HSD17B2RXFP1LTB4R2MAPT | |
| SCHEMBL5491797 | 0.75 | CES2 (0.47) | HSD17B1HSD17B2RXFP1MAPTHTT | |
| SCHEMBL11174926 | 0.74 | TACR1 (0.50) | HSD17B1HSD17B2RXFP1MAPTHTT | |
| SCHEMBL12220665 | 0.74 | RXFP1 (0.54) | HSD17B1HSD17B2RXFP1MAPTHTT | |
| SCHEMBL4461612 | 0.73 | ATM (0.45) | HSD17B1HSD17B2RXFP1LTB4R2MAPT | |
| SCHEMBL12544171 | 0.72 | NR1H3 (0.57) | HSD17B1HSD17B2RXFP1MAPTHTT | |
| SCHEMBL16388049 | 0.72 | KIF11 (0.52) | LTB4R2SERPINE1KIF11 | |
| SCHEMBL28141847 | 0.72 | TP53 (0.50) | HSD17B1HSD17B2RXFP1MAPTHTT | |
| SCHEMBL11536412 | 0.71 | TP53 (0.42) | RXFP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL21631301 | 0.71 | ROCK2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018135918-A1 | PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BLT INHIBITING ACTIVITY AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 동국대학교 산학협력단 | 2018-07-26 | — | — | WO | disclosed |