Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.64 |
| ▸ | HTR2A | P28223 | 8/20 | 0.64 |
| ▸ | HTR1A | P08908 | 7/20 | 0.64 |
| ▸ | HTR2C | P28335 | 4/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.64 |
| ▸ | HRH1 | P35367 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | DGKA | P23743 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10945457 | 0.84 | HTR1A (0.64) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| Hydrochloric Acid SCHEMBL10923635 | 0.83 | DRD2 (0.70) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| SCHEMBL15999621 | 0.83 | HTR1A (0.65) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| SCHEMBL10926120 | 0.78 | CYP2D6 (0.70) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| SCHEMBL7407787 | 0.78 | CYP2D6 (0.59) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| Ritanserin SCHEMBL49227 | 0.78 | MAPT (1.00) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| Ritanserin SCHEMBL10598671 | 0.77 | MAPT (0.98) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| SCHEMBL10919317 | 0.77 | HTR2C (0.73) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| SCHEMBL8804386 | 0.76 | PKM (0.62) | DRD2HTR2AHTR1AHTR2CCYP2D6 | |
| SCHEMBL316891 | 0.75 | MAPT (1.00) | DRD2HTR2AHTR1AHTR2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10028922-B2 | Method for enhancing folding and transport of misfolded glucocerebrosidase | THE HOSPITAL FOR SICK CHILDREN (CA) | 2018-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028922-B2 | Method for enhancing folding and transport of misfolded glucocerebrosidase | GBA1, GBA3, GAA | DRD2 4459/4885HTR2A 4146/4885HTR1A 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.