Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTR2C | P28335 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | DGKA | P23743 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999621 | 0.88 | HTR1A (0.65) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| SCHEMBL10919317 | 0.79 | HTR2C (0.73) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| SCHEMBL20402682 | 0.78 | DRD2 (0.64) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| SCHEMBL7142123 | 0.75 | HTR2A (0.59) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| Ritanserin SCHEMBL49227 | 0.74 | MAPT (1.00) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| SCHEMBL8804386 | 0.74 | PKM (0.62) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| Hydrochloric Acid SCHEMBL9871521 | 0.74 | HTR2C (0.65) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| Ritanserin SCHEMBL10598671 | 0.74 | MAPT (0.98) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| SCHEMBL7283740 | 0.74 | DRD2 (0.66) | CYP2D6TSHRPKMSMN1; SMN2HTR2C | |
| Hydrochloric Acid SCHEMBL10945457 | 0.73 | HTR1A (0.64) | CYP2D6TSHRPKMSMN1; SMN2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |