Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395497 | 0.81 | CARM1 (0.47) | PDE10ACARM1PRMT6DRD1GCK | |
| SCHEMBL20406531 | 0.78 | PDE10A (0.58) | MAOBPDE10ADRD1KMT2ATDP1 | |
| SCHEMBL20406295 | 0.77 | CARM1 (0.43) | PDE10ACARM1PRMT6DRD1GCK | |
| SCHEMBL20406235 | 0.75 | MAPT (0.47) | PDE10ACARM1PRMT6KMT2ARAB9A | |
| SCHEMBL4009097 | 0.73 | TRPA1 (0.52) | PDE10ACARM1DRD1GCKRAB9A | |
| SCHEMBL31395515 | 0.73 | PDE10A (0.53) | PDE10ADRD1KMT2A | |
| SCHEMBL27653432 | 0.72 | TDP1 (0.62) | CARM1PRMT6DRD1KMT2ATDP1 | |
| SCHEMBL7674701 | 0.72 | KMT2A (0.64) | KMT2ATDP1RAB9A | |
| SCHEMBL25216729 | 0.72 | PDE10A (0.47) | MAOBPDE10ADRD1GCKKMT2A | |
| SCHEMBL20406258 | 0.72 | DRD1 (0.56) | PDE10ADRD1GCKKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |