Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007180 | 0.84 | TRPA1 (0.57) | TRPA1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4006790 | 0.82 | HTR1A (0.56) | TRPA1RAB9AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL20406612 | 0.80 | PDE10A (0.48) | RAB9AL3MBTL1PDE10AMAPTDRD1 | |
| SCHEMBL31395497 | 0.79 | CARM1 (0.47) | TRPA1EGFRKDRPDE10ADRD1 | |
| SCHEMBL4012114 | 0.78 | TRPA1 (0.49) | TRPA1RAB9AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL20406236 | 0.78 | HTR1A (0.39) | TRPA1KDRHTR1ASLC6A2SLC6A4 | |
| SCHEMBL20406235 | 0.77 | MAPT (0.47) | RAB9AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28115716 | 0.77 | TRPA1 (0.48) | TRPA1RAB9AL3MBTL1 | |
| SCHEMBL4009120 | 0.75 | HTR1A (0.47) | RAB9AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4008185 | 0.75 | PDE10A (0.44) | TRPA1HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |