Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928127 | 0.83 | LMNA (0.56) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL3346369 | 0.80 | CA12 (0.43) | SMN1; SMN2NPC1POLBRAB9AMIF | |
| SCHEMBL3346366 | 0.80 | CA12 (0.43) | SMN1; SMN2NPC1POLBRAB9AMIF | |
| SCHEMBL3346360 | 0.80 | CA12 (0.43) | SMN1; SMN2NPC1POLBRAB9AMIF | |
| SCHEMBL5509327 | 0.77 | CTSL (0.47) | CTRB1 | |
| SCHEMBL5764892 | 0.77 | POLB (0.60) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL5764894 | 0.75 | POLB (0.58) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL10389707 | 0.75 | POLB (0.62) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL7050438 | 0.75 | PLAU (0.50) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL8775648 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326655-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | Pharmaleads (FR) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010010106-A1 | AMINOPHOSPHINIC DERIVATIVES THAT CAN BE USED IN THE TREATMENT OF PAIN | PHARMALEADS (FR) | 2010-01-28 | — | — | WO | disclosed |