Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764894 | 0.95 | POLB (0.58) | POLBMGLLNPC1RAB9ATP53 | |
| SCHEMBL27614624 | 0.85 | L3MBTL1 (0.59) | POLBMGLLNPC1RAB9ATP53 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.82 | POLB (0.78) | POLBMGLLNPC1RAB9ATP53 | |
| SCHEMBL10595799 | 0.79 | POLB (0.73) | POLBMGLLNPC1RAB9ATP53 | |
| Benzyl Phenylcarbamate SCHEMBL2635177 | 0.78 | POLB (0.71) | POLBMGLLNPC1RAB9ATP53 | |
| SCHEMBL1870929 | 0.78 | POLB (0.71) | POLBMGLLNPC1RAB9ATP53 | |
| SCHEMBL2040848 | 0.77 | ALDH1A1 (0.47) | POLBMGLLNPC1RAB9AMAPT | |
| SCHEMBL10598558 | 0.76 | POLB (0.69) | POLBMGLLNPC1RAB9ATP53 | |
| SCHEMBL655257 | 0.76 | MGLL (0.66) | POLBMGLLNPC1RAB9ATP53 | |
| SCHEMBL9459601 | 0.76 | MGLL (0.66) | POLBMGLLNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732923-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005099706-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-10-27 | — | — | WO | disclosed |