Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.56 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 6/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | CPA2 | P48052 | 1/20 | 0.47 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101424 | 0.87 | SSTR3 (0.54) | CALCRLSSTR3MMP3MMP1MMP9 | |
| SCHEMBL13684815 | 0.87 | SSTR3 (0.56) | CALCRLSSTR3MMP3MMP1GNPAT | |
| SCHEMBL14821040 | 0.86 | SSTR3 (0.55) | CALCRLSSTR3MMP3LTA4H | |
| SCHEMBL18494988 | 0.86 | SSTR3 (0.55) | CALCRLSSTR3MMP3LTA4H | |
| SCHEMBL17706674 | 0.86 | SSTR3 (0.55) | CALCRLSSTR3MMP3LTA4H | |
| SCHEMBL14872058 | 0.84 | SSTR3 (0.55) | CALCRLSSTR3MMP3LTA4H | |
| SCHEMBL14821599 | 0.83 | MMP1 (0.57) | MMP3MMP1MMP9GNPAT | |
| SCHEMBL12245289 | 0.83 | SSTR3 (0.53) | CALCRLSSTR3MMP3MMP1PLG | |
| SCHEMBL22096459 | 0.82 | SSTR3 (0.51) | CALCRLSSTR3MMP3MMP1MMP9 | |
| SCHEMBL25083563 | 0.82 | CALCRL (0.56) | CALCRLSSTR3CPA1CPA2CPA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287256-B2 | Selective sulfonation of benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-20180208562-A1 | Selective Sulfonation of Benzodiazepine Derivatives | IMMUNOGEN, INC. | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208562-A1 | Selective Sulfonation of Benzodiazepine Derivatives | GABRA2, GABRA4, GABRA1 | CALCRL 3719/4885SSTR3 1428/4885MMP3 4864/4885 |
| US-10287256-B2 | Selective sulfonation of benzodiazepine derivatives | GABRA2, GABRA4, GABRA1 | CALCRL 3719/4885SSTR3 1428/4885MMP3 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.