SCHEMBL204208

SCHEMBL204208

CC(C)=C(C(=O)O)c1ccccc1Oc1cccc(C(O)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.44
CTNNB1 P35222 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2D6 P10635 1/20 0.40
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
ALOX5 P09917 1/20 0.39
SRD5A2 P31213 1/20 0.39
GAA P10253 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.38
NPY5R Q15761 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
RAB9A P51151 1/20 0.37
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204209 0.89 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL7759486 0.89 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL2851745 0.82 PTGS1 (0.44) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL203717 0.82 CTNNB1 (0.59) CTNNB1MEN1KMT2AGAATSHR
SCHEMBL203988 0.82 KDM4E (0.44) PTGS1CTNNB1MEN1KMT2AKDM4E
SCHEMBL202625 0.82 KDM4E (0.59) CTNNB1MEN1KMT2AKDM4EPOLB
SCHEMBL31289592 0.80 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL2851748 0.80 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL17927792 0.80 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL2851743 0.80 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 US disclosed
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF MERIAL, INC. 2010-09-30 US disclosed
EP-1755841-B1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES OSMOSE INC (US) 2010-09-15 EP disclosed
US-20090293761-A1 Composition for wood treatment comprising an injectable aqueous wood preservative slurry having sparingly-soluble biocidal particles and pigments OSMOSE, INC. 2009-12-03 US disclosed
EP-1796885-A1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES Phibro-Tech, Inc. (US) 2007-06-20 EP disclosed
EP-0820370-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1998-01-28 EP disclosed
EP-0750542-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AG (DE) 1997-01-02 EP disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 WO disclosed
EP-0736075-A1 ANTI-FOULING AGENT BAYER AG (DE) 1996-10-09 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
EP-0690894-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AG (DE) 1996-01-10 EP disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995017478-A1 ANTI-FOULING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 PTGS1 2107/4885CTNNB1 4184/4885MEN1 3084/4885
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 PTGS1 1443/4885CTNNB1 4705/4885MEN1 2747/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 PTGS1 3970/4885CTNNB1 3217/4885MEN1 420/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 PTGS1 2107/4885CTNNB1 4184/4885MEN1 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.