SCHEMBL7759486

SCHEMBL7759486

CO/C(C)=C(/C(=O)O)c1ccccc1Oc1cccc(C(O)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
RAB9A P51151 1/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MTNR1B P49286 3/20 0.39
CTNNB1 P35222 1/20 0.39
CASP1 P29466 1/20 0.39
CYP2D6 P10635 1/20 0.38
MTNR1A P48039 2/20 0.38
NPY5R Q15761 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204209 1.00 PTGS1 (0.41) PTGS1RAB9AKDM4EPOLBMEN1
SCHEMBL204208 0.89 PTGS1 (0.44) PTGS1RAB9AKDM4EPOLBMEN1
SCHEMBL202626 0.84 KDM4E (0.57) RAB9AKDM4EPOLBMEN1KMT2A
SCHEMBL203718 0.84 CTNNB1 (0.54) RAB9AKDM4EMEN1KMT2ACTNNB1
SCHEMBL203989 0.83 KDM4E (0.44) RAB9AKDM4EPOLBMEN1KMT2A
SCHEMBL9155384 0.82 SIRT2 (0.47) RAB9AKDM4EPOLBMEN1KMT2A
SCHEMBL8798837 0.81 MAPT (0.36) POLBLMNAHTT
SCHEMBL204355 0.81 L3MBTL1 (0.44) RAB9AKDM4EPOLBMEN1KMT2A
SCHEMBL203538 0.80 LMNA (0.51) RAB9AKDM4EPOLBMTNR1BL3MBTL1
SCHEMBL2851745 0.80 PTGS1 (0.44) PTGS1RAB9AKDM4EPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082014-A1 SYNERGISTIC INSECTICIDE MIXTURESANTISENSE OLIGONUCLEOTIDES FOR TREATING PROLIFERATING CELLS Bayer Aktiengesellschaft (DE) 2001-03-14 EP disclosed
WO-1999060857-A1 SYNERGISTIC INSECTICIDE MIXTURESANTISENSE OLIGONUCLEOTIDES FOR TREATING PROLIFERATING CELLS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-02 WO disclosed
EP-0871362-A1 SYNERGISTIC INSECTICIDE MIXTURES BAYER AG (DE) 1998-10-21 EP disclosed
EP-0865436-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AG (DE) 1998-09-23 EP disclosed
EP-0847386-A1 N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION BAYER AG (DE) 1998-06-17 EP disclosed
EP-0815085-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1998-01-07 EP disclosed
EP-0785718-A1 INSECTICIDES BAYER AG (DE) 1997-07-30 EP disclosed
WO-1997024032-A1 SYNERGISTIC INSECTICIDE MIXTURES BAYER AKTIENGESELLSCHAFT (DE) 1997-07-10 WO disclosed
WO-1997020830-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-06-12 WO disclosed
WO-1997008140-A1 N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed
WO-1996029314-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1996-09-26 WO disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed
EP-0726710-A1 STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION BAYER AG (DE) 1996-08-21 EP disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 WO disclosed
WO-1995012315-A1 STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1995-05-11 WO disclosed