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SCHEMBL2851748

SCHEMBL2851748

COC=C(C(=O)O)c1ccccc1Oc1cccc(C(O)c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ CTNNB1 P35222 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ ALOX5 P09917 1/20 0.37
▸ SRD5A2 P31213 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ NPY5R Q15761 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2851743 1.00 PTGS1 (0.41) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL31289592 1.00 PTGS1 (0.41) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL17927792 1.00 PTGS1 (0.41) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL29359432 0.91 PTGS1 (0.40) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL9148463 0.91 PTGS1 (0.40) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL204207 0.91 PTGS1 (0.40) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL2851745 0.89 PTGS1 (0.44) PTGS1KDM4EPOLBCTNNB1CASP1
SCHEMBL2107591 0.84 KDM4E (0.57) KDM4EPOLBCTNNB1MEN1KMT2A
SCHEMBL2107595 0.84 KDM4E (0.57) KDM4EPOLBCTNNB1MEN1KMT2A
SCHEMBL2855935 0.84 KDM4E (0.57) KDM4EPOLBCTNNB1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 — — US disclosed
US-20240041028-A1 DELIVERY SYSTEM FOR PLANT PROTECTION OMYA INTERNATIONAL AG (CH) 2024-02-08 — — US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 — — US disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 — — US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 — — EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 — — EP disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 — — EP disclosed
US-11629129-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
US-6893651-B1 Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants BAYER AKTIENGESELLSCHAFT (DE) 2005-05-17 — — US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 — — US disclosed
US-20040127520-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2004-07-01 — — US disclosed
US-6686387-B2 SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 — — US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 — — US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 — — US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 — — US disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 — — EP disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 — — US disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 PTGS1 2833/4885KDM4E 3852/4885POLB 4880/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 PTGS1 2038/4885KDM4E 2462/4885POLB 3401/4885
US-20040127520-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 PTGS1 2833/4885KDM4E 3852/4885POLB 4880/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG PTGS1 1557/4885KDM4E 3260/4885POLB 3655/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 PTGS1 1156/4885KDM4E 2885/4885POLB 2340/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 PTGS1 780/4885KDM4E 2969/4885POLB 3534/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 PTGS1 2594/4885KDM4E 4050/4885POLB 4375/4885
US-11629129-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, MSR1 PTGS1 808/4885KDM4E 3192/4885POLB 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.