Sugi Predict

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SCHEMBL2851745

SCHEMBL2851745

C/C=C(/C(=O)O)c1ccccc1Oc1cccc(C(O)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.44
▸ CTNNB1 P35222 1/20 0.41
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CASP1 P29466 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ ALOX5 P09917 1/20 0.39
▸ SRD5A2 P31213 1/20 0.39
▸ NPY5R Q15761 1/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ MTNR1B P49286 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17927792 0.89 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL31289592 0.89 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL2851748 0.89 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL2851743 0.89 PTGS1 (0.41) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL204208 0.82 PTGS1 (0.44) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL29359432 0.82 PTGS1 (0.40) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL9148463 0.82 PTGS1 (0.40) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL204207 0.82 PTGS1 (0.40) PTGS1CTNNB1MEN1KMT2ACYP2D6
SCHEMBL2106716 0.82 CTNNB1 (0.59) CTNNB1MEN1KMT2APOLBL3MBTL1
SCHEMBL2847810 0.82 CTNNB1 (0.59) CTNNB1MEN1KMT2APOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 — — US disclosed
US-20240041028-A1 DELIVERY SYSTEM FOR PLANT PROTECTION OMYA INTERNATIONAL AG (CH) 2024-02-08 — — US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 — — US disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 — — US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 — — EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 — — EP disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 — — EP disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
US-11629129-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
US-7001903-B2 Synergistic insecticidal mixtures BAYER AKTIENGESELLSCHAFT (DE) 2006-02-21 — — US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 — — US disclosed
US-20040127520-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2004-07-01 — — US disclosed
US-6686387-B2 SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 — — US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 — — US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 — — US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 — — US disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 — — EP disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 — — US disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 PTGS1 2833/4885CTNNB1 3858/4885MEN1 3394/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 PTGS1 2038/4885CTNNB1 4410/4885MEN1 2194/4885
US-20040127520-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 PTGS1 2833/4885CTNNB1 3858/4885MEN1 3394/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG PTGS1 1557/4885CTNNB1 4135/4885MEN1 2895/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 PTGS1 1156/4885CTNNB1 2621/4885MEN1 2306/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 PTGS1 780/4885CTNNB1 4630/4885MEN1 3561/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 PTGS1 2594/4885CTNNB1 4851/4885MEN1 502/4885
US-11629129-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, MSR1 PTGS1 808/4885CTNNB1 4671/4885MEN1 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.