Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424771 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TRIM24TYRTRIM33KMT2A | |
| SCHEMBL17871817 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TRIM24TYRTRIM33KMT2A | |
| SCHEMBL20525235 | 0.80 | TRIM24 (0.46) | FFAR1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL27143572 | 0.79 | CES2 (0.49) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL17871823 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TRIM24TYRTRIM33KMT2A | |
| SCHEMBL17871965 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TRIM24TYRTRIM33KMT2A | |
| SCHEMBL20424635 | 0.79 | FFAR1 (0.35) | FFAR1ALDH1A1DRD2DRD3KCNH2 | |
| SCHEMBL20424634 | 0.79 | FFAR1 (0.35) | FFAR1ALDH1A1DRD2DRD3KCNH2 | |
| SCHEMBL24646041 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TRIM24TYRTRIM33KMT2A | |
| SCHEMBL20424922 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TRIM24TYRTRIM33KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573972-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2026-01-14 | — | — | EP | disclosed |
| US-11077115-B2 | Rorgamma modulators and uses thereof | GENFIT (FR) | 2021-08-03 | — | — | US | disclosed |
| WO-2018138359-A1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2018-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077115-B2 | Rorgamma modulators and uses thereof | RORB, RORC, RORA | FFAR1 299/4885ALDH1A1 761/4885TRIM24 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.