Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054202 | 0.84 | LDHA (0.62) | RXFP1NPC1LDHABAZ2BSMN1; SMN2 | |
| SCHEMBL16991665 | 0.82 | NPC1 (0.51) | RXFP1KDM1ANPC1LDHABAZ2B | |
| SCHEMBL23110059 | 0.80 | RXFP1 (0.40) | RXFP1KDM1ANPC1LDHACCR1 | |
| SCHEMBL27702582 | 0.80 | NPC1 (0.67) | RXFP1KDM1ANPC1LDHACCR1 | |
| SCHEMBL5428820 | 0.79 | LDHA (0.71) | RXFP1NPC1LDHABAZ2BSMN1; SMN2 | |
| SCHEMBL12647420 | 0.77 | HPGDS (0.55) | RXFP1KDM1ANPC1LDHABAZ2B | |
| SCHEMBL20428452 | 0.77 | KDM1A (0.46) | RXFP1KDM1ANPC1LDHACCR1 | |
| SCHEMBL2477927 | 0.76 | CCR1 (0.71) | KDM1ANPC1CCR1CCR5CCR8 | |
| SCHEMBL94501 | 0.76 | ALDH1A1 (0.52) | NPC1HDAC6SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL21033709 | 0.75 | TDP1 (0.59) | RXFP1NPC1LDHABAZ2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |