Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE6A | P16499 | 1/20 | 0.35 |
| ▸ | PDE6G | P18545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE6B | P35913 | 1/20 | 0.35 |
| ▸ | PDE6C | P51160 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316287 | 0.81 | ALDH1A1 (0.35) | TSHRATMNOD1MAPTMEN1 | |
| SCHEMBL19505598 | 0.68 | NOD1 (0.32) | PDE5ALMNANOD1MEN1KMT2A | |
| SCHEMBL22105780 | 0.67 | ALDH1A1 (0.38) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20432346 | 0.65 | P2RX3 (0.35) | POLBTSHRP2RX3 | |
| SCHEMBL21889017 | 0.64 | LMNA (0.38) | POLBTSHRATMAPOBEC3GGALR3 | |
| SCHEMBL21499649 | 0.64 | MAPK1 (0.43) | POLBTSHRLMNAMAPTMEN1 | |
| SCHEMBL16028621 | 0.63 | ATM (0.71) | POLBTSHRATMAPOBEC3GLMNA | |
| SCHEMBL16029542 | 0.62 | ALDH1A1 (0.70) | POLBTSHRATMRAB9ALMNA | |
| SCHEMBL21332695 | 0.62 | KDM4E (0.42) | POLBTSHRPDE4DGALR3NR2F2 | |
| SCHEMBL10506664 | 0.61 | PNP (0.60) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |