Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505327 | 0.67 | HTT (0.35) | LMNAMAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16028820 | 0.64 | ATM (0.71) | LMNAMAPTPOLBATMAPOBEC3G | |
| SCHEMBL9681986 | 0.62 | NPSR1 (0.50) | LMNAMAPTPOLBRAB9AGALR3 | |
| SCHEMBL17814738 | 0.62 | TNF (0.42) | LMNAMAPTPOLBRAB9AGALR3 | |
| SCHEMBL9701321 | 0.62 | TBXA2R (0.53) | LMNAMAPTRAB9AGALR3NR2F2 | |
| SCHEMBL21389540 | 0.61 | BRD4 (0.62) | MAPTPOLBATMAPOBEC3GSMN1; SMN2 | |
| SCHEMBL11719377 | 0.61 | P2RX3 (0.54) | LMNAMAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL17814735 | 0.61 | PNP (0.57) | KMT2A | |
| SCHEMBL9682976 | 0.61 | NOD1 (0.40) | LMNAMAPTPOLBRAB9AGALR3 | |
| SCHEMBL6674154 | 0.60 | GRM2 (0.36) | LMNAPOLBATMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10617723-B2 | C. novyi for the treatment of solid tumors in humans | BIOMED VALLEY DISCOVERIES, INC. (US) | 2020-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617723-B2 | C. novyi for the treatment of solid tumors in humans | HCCS, MKI67, PBK | LMNA 2128/4885MAPT 4509/4885POLB 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.