SCHEMBL204334

SCHEMBL204334

CCCc1ccc(-c2ccccc2C(=O)N2CCS(=O)(=O)C2C(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
PPARG P37231 2/20 0.39
FFAR2 O15552 1/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201720 0.89 LMNA (0.39) LMNAPPARGSCN1ASCN2ASCN3A
SCHEMBL201902 0.80 FFAR2 (0.42) LMNAPPARGFFAR2
SCHEMBL201735 0.78 LMNA (0.42) LMNAPPARGFFAR2TSHRRECQL
SCHEMBL201372 0.77 PPARG (0.42) LMNAPPARGTSHRRECQL
SCHEMBL203045 0.77 LMNA (0.41) LMNAPPARGFFAR2TSHRRECQL
SCHEMBL201577 0.76 LMNA (0.40) LMNAPPARGTSHRRECQL
SCHEMBL202879 0.75 ACE (0.44) LMNAPPARGFFAR2
SCHEMBL203290 0.75 LMNA (0.42) LMNAPPARGFFAR2SCN1ASCN2A
SCHEMBL202908 0.74 AGTR1 (0.37) LMNAPPARGFFAR2
SCHEMBL3230323 0.72 LTB4R2 (0.63) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088804-B2 N-hydroxyamide derivatives possessing antibacterial activity PFIZER INC. (US) 2012-01-03 US disclosed
EP-2338878-A2 N-hydroxyamide derivatives possessing antibacterial activity Vicuron Pharmaceuticals, Inc. (US) 2011-06-29 EP disclosed
US-20100022605-A1 N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022605-A1 N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY NAAA, HDHD5, HACL2 LMNA 1020/4885PPARG 2254/4885FFAR2 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.