Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23481362 | 0.87 | KMT2A (0.54) | KMT2AMEN1ALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL22794783 | 0.85 | MMP8 (0.49) | KMT2AMEN1MMP8MAPT | |
| SCHEMBL21107013 | 0.85 | MMP8 (0.49) | KMT2AMEN1MMP8MAPT | |
| SCHEMBL13668152 | 0.84 | KMT2A (0.57) | KMT2AMEN1ALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL21107012 | 0.84 | KMT2A (0.46) | KMT2AMEN1ALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL23807034 | 0.83 | EPHX1 (0.50) | EPHX2MMP8 | |
| SCHEMBL25128845 | 0.83 | KMT2A (0.45) | KMT2AMEN1ALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL23807051 | 0.83 | KMT2A (0.49) | KMT2AMEN1ALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL27268363 | 0.82 | KMT2A (0.47) | KMT2AMEN1ALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL22799828 | 0.81 | DPP7 (0.50) | KMT2AMEN1EPHX2MMP8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730892-B2 | Homoallylamines as formaldehyde-responsive triggers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20180215773-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-02 | — | — | US | disclosed |
| US-20180215773-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215773-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | HCAR2, HCAR1, HTR2A | KMT2A 1693/4885MEN1 3183/4885ALDH1A1 1031/4885 |
| US-10730892-B2 | Homoallylamines as formaldehyde-responsive triggers | HCAR2, MTHFD2, AHCY | KMT2A 1353/4885MEN1 2880/4885ALDH1A1 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.