Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855399 | 0.87 | TDP1 (0.39) | TSHRTDP1MAPT | |
| SCHEMBL5855412 | 0.87 | TDP1 (0.39) | TSHRTDP1MAPT | |
| SCHEMBL17375167 | 0.85 | ALDH1A1 (0.41) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8072983 | 0.85 | TAAR1 (0.33) | TRPA1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL21069311 | 0.82 | POLB (0.35) | TSHRMAPT | |
| SCHEMBL22609367 | 0.82 | POLB (0.35) | TSHRMAPT | |
| SCHEMBL24111210 | 0.81 | LTA4H (0.46) | CYP1A2 | |
| SCHEMBL6118654 | 0.80 | IDO1 (0.35) | TAAR1TSHRCTSK | |
| SCHEMBL16414460 | 0.79 | MMP12 (0.38) | TRPA1TSHRTDP1MAPT | |
| SCHEMBL16414459 | 0.79 | MMP12 (0.38) | TRPA1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140738-A1 | NRF 2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |