SCHEMBL2043682

SCHEMBL2043682

CC(C)c1c(N)ccc(Cc2ccc(N)c(C(C)C)c2C(C)C)c1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
GAA P10253 2/20 0.33
HTT P42858 2/20 0.33
HIF1A Q16665 2/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX12 P18054 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL924270 0.84 ALDH1A1 (0.37) ALDH1A1GAAHTTHIF1ATSHR
SCHEMBL4961322 0.82 CYP3A4 (0.37) ALDH1A1HIF1ATSHRCYP1A2ALOX15
SCHEMBL841650 0.79 USP2 (0.38) ALDH1A1GAATSHRALOX15HSD17B10
SCHEMBL9576008 0.77 SLC6A2 (0.36) TSHRALOX15CASP7SLC6A2SLC6A4
SCHEMBL616037 0.76 P2RX3 (0.33) GAAHTTMAPTTSHRMAPK1
SCHEMBL616248 0.76 POLB (0.37) ALDH1A1GAAHTTHIF1AMAPT
SCHEMBL1532606 0.73 CYP3A4 (0.37) ALDH1A1GAAHTTHIF1AMAPT
SCHEMBL1228797 0.73 LMNA (0.32) ALDH1A1GAAHTTHIF1ATSHR
SCHEMBL8061888 0.73 CYP3A4 (0.43) ALDH1A1GAAMAPTTSHR
SCHEMBL939779 0.72 CD44 (0.35) ALDH1A1GAAHTTHIF1AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3919542-B1 FAST CURE EPOXY RESIN COMPOSITIONS CYTEC ENGINEERED MAT LTD (GB) 2023-03-15 EP disclosed
US-20220227967-A1 Coloured material based on metal nanoparticles Universite de Bordeaux (FR) 2022-07-21 US disclosed
EP-3919542-A1 FAST CURE EPOXY RESIN COMPOSITIONS Cytec Industrial Materials (Derby) Limited (GB) 2021-12-08 EP disclosed
US-11078320-B2 Porous materials based on aromatic amines BASF SE (DE) 2021-08-03 US disclosed
US-10717808-B2 Fast cure epoxy resin compositions CYTEC ENGINEERED MATERIALS LIMITED (GB) 2020-07-21 US disclosed
US-20190010275-A1 FAST CURE EPOXY RESIN COMPOSITIONS CYTEC ENGINEERED MATERIALS LIMITED (GB) 2019-01-10 US disclosed
US-10093768-B2 Fast cure epoxy resin compositions CYTEC INDUSTRIAL MATERIALS (DERBY) LIMITED (GB) 2018-10-09 US disclosed
EP-3303441-A1 FAST CURE EPOXY RESIN COMPOSITIONS Cytec Industrial Materials (Derby) Limited (GB) 2018-04-11 EP disclosed
WO-2016193821-A1 FAST CURE EPOXY RESIN COMPOSITIONS CYTEC INDUSTRIAL MATERIALS (DERBY) LIMITED (GB) 2016-12-08 WO disclosed
US-20160355635-A1 FAST CURE EPOXY RESIN COMPOSITIONS CYTEC INDUSTRIAL MATERIALS (DERBY) LIMITED (GB) 2016-12-08 US disclosed
US-20120305827-A1 POROUS MATERIALS BASED ON AROMATIC AMINES BASF SE (DE) 2012-12-06 US disclosed
EP-2510026-A2 IMPROVED POROUS MATERIALS BASED ON AROMATIC AMINES BASF SE (DE) 2012-10-17 EP disclosed
WO-2011123223-A1 POLYURETHANE COMPOSITIONS HAVING IMPROVED IMPACT RESISTANCE AND OPTICAL PROPERTIES Dow Global Technologies LLC (Formerly known as Dow Global Technologies Inc.) (US) 2011-10-06 WO disclosed
WO-2011069959-A2 IMPROVED POROUS MATERIALS BASED ON AROMATIC AMINES BASF SE (DE) 2011-06-16 WO disclosed
WO-2005108961-A9 METHOD FOR MARKING TERRAIN LANXESS DEUTSCHLAND GMBH (DE) 2006-10-26 WO disclosed
WO-2002064658-A1 LOW COST, RESILIENT, SHEAR RESISTANT POLYURETHANE ELASTOMERS FOR GOLF BALL COVERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-08-22 WO disclosed
EP-0657482-A1 Process for the preparation of compact or cellular polyurethanes, urethane group containing polyisocyanate compositions and their use in this process BASF AKTIENGESELLSCHAFT (DE) 1995-06-14 EP disclosed
EP-0409433-A1 Internal mould release compositions ATLAS EUROPOL SpA (IT) 1991-01-23 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
EP-0026915-A2 Process for preparing moulded polyurethane-polyurea articles which may contain cells BASF Aktiengesellschaft (DE) 1981-04-15 EP disclosed