SCHEMBL616248

SCHEMBL616248

Cc1ccc(Cc2ccc(C)c(N)c2C(C)C)c(C(C)C)c1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
ALDH1A1 P00352 5/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP7 P55210 1/20 0.34
HIF1A Q16665 1/20 0.34
CD44 P16070 1/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 2/20 0.32
NPC1 O15118 1/20 0.32
CYP3A4 P08684 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
HBB P68871 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NOS3 P29474 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL616037 0.79 P2RX3 (0.33) TSHRMAPK1GAAMAPTHTT
SCHEMBL6357268 0.76 POLB (0.41) POLBALDH1A1HSD17B10ALOX15CD44
SCHEMBL2043682 0.76 ALDH1A1 (0.33) ALDH1A1HSD17B10CYP1A2ALOX15CASP7
SCHEMBL1259716 0.73 POLB (0.54) POLBALDH1A1HSD17B10CYP1A2ALOX15
SCHEMBL669696 0.72 CYP3A4 (0.40) POLBALDH1A1HSD17B10CYP1A2CD44
SCHEMBL7555970 0.71 DHFR (0.41)
SCHEMBL166574 0.71 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1A2ALOX15CASP7
SCHEMBL12339824 0.71 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1A2ALOX15CASP7
SCHEMBL6320495 0.69 POLB (0.42) POLBALDH1A1HSD17B10CYP1A2ALOX15
SCHEMBL4961322 0.68 CYP3A4 (0.37) ALDH1A1HSD17B10CYP1A2ALOX15CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535686-B2 Tough, high temperature polymers produced by stereolithography CARBON, INC. (US) 2022-12-27 US claimed
EP-3441411-B1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF POLYMER SOLUTIONS GMBH & CO KG (DE) 2022-02-09 EP claimed
EP-3441410-A1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF Holding GmbH & Co. KG (DE) 2019-02-13 EP claimed
EP-3441411-A1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF Holding GmbH & Co. KG (DE) 2019-02-13 EP claimed
US-8779036-B2 Catalysis of epoxy resin formulations EVONIK DEGUSSA GMBH (DE) 2014-07-15 US claimed
US-20120115988-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS HAVING SPARINGLY SOLUBLE CATALYSTS EVONIK DEGUSSA GMBH (DE) 2012-05-10 US claimed
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
US-11834574-B2 Dual cure additive manufacturing resins for production of flame retardant objects CARBON, INC. (US) 2023-12-05 US disclosed
US-11814472-B2 Epoxy dual cure resins for additive manufacturing CARBON, INC. (US) 2023-11-14 US disclosed
US-20230143277-A1 DUAL CURE STEREOLITHOGRAPHY RESINS CONTAINING DIELS-ALDER ADDUCTS CARBON INC (US) 2023-05-11 US disclosed
US-11629202-B2 Dual cure stereolithography resins containing thermoplastic particles CARBON, INC. (US) 2023-04-18 US disclosed
EP-3849806-B1 DUAL CURE ADDITIVE MANUFACTURING RESINS FOR PRODUCTION OF FLAME RETARDANT OBJECTS CARBON INC (US) 2023-04-05 EP disclosed
US-20230095097-A1 TOUGH, HIGH TEMPERATURE POLYMERS PRODUCED BY STEREOLITHOGRAPHY CARBON INC (US) 2023-03-30 US disclosed
WO-2018129023-A1 DUAL CURE STEREOLITHOGRAPHY RESINS CONTAINING DIELS-ALDER ADDUCTS CARBON, INC. (US) 2018-07-12 WO disclosed
EP-3341792-A1 DUAL PRECURSOR RESIN SYSTEMS FOR ADDITIVE MANUFACTURING WITH DUAL CURE RESINS Carbon, Inc. (US) 2018-07-04 EP disclosed
US-20180171066-A1 STORAGE-STABLE IMPREGNATING RESINS AND ELECTRICAL INSULATING TAPES SIEMENS AKTIENGESELLSCHAFT (DE) 2018-06-21 US disclosed
US-8779036-B2 Catalysis of epoxy resin formulations EVONIK DEGUSSA GMBH (DE) 2014-07-15 US disclosed
WO-2012121997-A1 POLYTHIOURETHAN BASED COMPOSITE ARTICLES PPG INDUSTRIES OHIO, INC. (US) 2012-09-13 WO disclosed
US-20120115988-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS HAVING SPARINGLY SOLUBLE CATALYSTS EVONIK DEGUSSA GMBH (DE) 2012-05-10 US disclosed
US-20120041101-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS EVONIK DEGUSSA GMBH (DE) 2012-02-16 US disclosed