SCHEMBL616037

SCHEMBL616037

CC(C)c1ccc(Cc2ccc(C(C)C)c(N)c2C(C)C)c(C(C)C)c1N

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 1/20 0.33
P2RX2 Q9UBL9 1/20 0.33
DHFR P00374 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7555970 0.89 DHFR (0.41) P2RX3P2RX2DHFR
SCHEMBL5673130 0.79 TRPA1 (0.32) GAAMAPTTSHRMAPK1HTT
SCHEMBL616248 0.79 POLB (0.37) GAAMAPTTSHRMAPK1HTT
SCHEMBL2043682 0.76 ALDH1A1 (0.33) GAAMAPTTSHRMAPK1HTT
SCHEMBL6751624 0.76 LMNA (0.31) GAATSHRHTT
SCHEMBL19505690 0.74 POLB (0.34) GAATSHR
SCHEMBL9879909 0.74 GABRA1 (0.39) GAATSHRHTT
SCHEMBL5575889 0.72 GABRA1 (0.43) TSHR
SCHEMBL6280677 0.72 PDE2A (0.32)
SCHEMBL10341257 0.72 LMNA (0.36) TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535686-B2 Tough, high temperature polymers produced by stereolithography CARBON, INC. (US) 2022-12-27 US claimed
EP-3441411-B1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF POLYMER SOLUTIONS GMBH & CO KG (DE) 2022-02-09 EP claimed
EP-3441411-A1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF Holding GmbH & Co. KG (DE) 2019-02-13 EP claimed
EP-3441410-A1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF Holding GmbH & Co. KG (DE) 2019-02-13 EP claimed
US-8779036-B2 Catalysis of epoxy resin formulations EVONIK DEGUSSA GMBH (DE) 2014-07-15 US claimed
US-20120115988-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS HAVING SPARINGLY SOLUBLE CATALYSTS EVONIK DEGUSSA GMBH (DE) 2012-05-10 US claimed
US-20120041101-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS EVONIK DEGUSSA GMBH (DE) 2012-02-16 US claimed
EP-0424076-B1 Chemorheologically tailored matrix resin formulations and their use in making pre-impregnated fibers and in fabricating composite parts THIOKOL CORP (US) 1995-12-20 EP claimed
EP-0122149-B1 METAL FLUOBORATE CATALYSED HINDERED AROMATIC AMINO CURING AGENTS FOR POLYEPOXIDE RESINS INTEREZ, Inc. (a Georgia corporation) (US) 1988-07-06 EP claimed
EP-0120666-B1 POLYGLYCIDYL HINDERED AROMATIC AMINES INTEREZ, Inc. (a Georgia corporation) (US) 1987-07-08 EP claimed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US claimed
US-4487948-A POLYEPOXIDES, HEAT RESISTANCE, STORAGE STABILITY CELANESE CORPORATION (US) 1984-12-11 US claimed
US-4447586-A Metal fluoborate catalyzed hindered aromatic amine curing agents for polyepoxide resins CELANESE CORPORATION (US) 1984-05-08 US claimed
US-11834574-B2 Dual cure additive manufacturing resins for production of flame retardant objects CARBON, INC. (US) 2023-12-05 US disclosed
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
US-11814472-B2 Epoxy dual cure resins for additive manufacturing CARBON, INC. (US) 2023-11-14 US disclosed
EP-0120666-A1 Polyglycidyl hindered aromatic amines INTEREZ, Inc. (a Georgia corporation) (US) 1984-10-03 EP disclosed
US-4447586-A Metal fluoborate catalyzed hindered aromatic amine curing agents for polyepoxide resins CELANESE CORPORATION (US) 1984-05-08 US disclosed
US-4324867-A FROM A POLYETHER, ISOCYANATE, DIAMINODIPHENYLALKANE MIXTURE BASF WYANDOTTE CORPORATION (US) 1982-04-13 US disclosed
EP-0026915-A2 Process for preparing moulded polyurethane-polyurea articles which may contain cells BASF Aktiengesellschaft (DE) 1981-04-15 EP disclosed