Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472095 | 0.86 | ALDH1A1 (0.43) | ALDH1A1OPRM1OPRD1OPRK1KDM4E | |
| Bromide SCHEMBL7202386 | 0.83 | ALDH1A1 (0.42) | ALDH1A1OPRM1OPRD1OPRK1KDM4E | |
| Fluoride SCHEMBL23302253 | 0.83 | ALDH1A1 (0.42) | ALDH1A1OPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL20438489 | 0.83 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20438365 | 0.81 | LMNA (0.41) | ALDH1A1LMNA | |
| SCHEMBL19543354 | 0.80 | CYP1A2 (0.43) | ALDH1A1OPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL13759584 | 0.80 | CYP1A2 (0.43) | ALDH1A1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL3409861 | 0.78 | PLA2G1B (0.39) | ALDH1A1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL436979 | 0.78 | PLA2G1B (0.39) | ALDH1A1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL12039787 | 0.75 | OPRM1 (0.37) | ALDH1A1OPRM1OPRD1OPRK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | ALDH1A1 1061/4885OPRM1 1710/4885OPRD1 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.